Publications

2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999以前

<2018>

Attardo A, Lu J, Kawashima T, Okuno H, Fitzgerald JE, Bito H, Schnitzer MJ.
Long-Term Consolidation of Ensemble Neural Plasticity Patterns in Hippocampal Area CA1. Cell reports 2018, October 25(3); 640-650.e2

Sonoda K, Matsui T, Bito H, Ohki K.
Astrocytes in the mouse visual cortex reliably respond to visual stimulation. Biochemical and biophysical research communications 2018, October 505(4); 1216-1222

Nishiguchi KM, Fujita K, Tokashiki N, Komamura H, Takemoto-Kimura S, Okuno H, Bito H, Nakazawa T.
Retained Plasticity and Substantial Recovery of Rod-Mediated Visual Acuity at the Visual Cortex in Blind Adult Mice with Retinal Dystrophy. Molecular therapy 2018, October 26(10); 2397-2406

Benner S, Aoki Y, Watanabe T, Endo N, Abe O, Kuroda M, Kuwabara H, Kawakubo Y, Takao H, Kunimatsu A, Kasai K, Bito H, Kakeyama M, Yamasue H.
Neurochemical evidence for differential effects of acute and repeated oxytocin administration. Molecular psychiatry 2018, September

Kikuchi K, Ihara D, Fukuchi M, Tanabe H, Ishibashi Y, Tsujii J, Tsuda M, Kaneda M, Sakagami H, Okuno H, Bito H, Yamazaki Y, Ishikawa M, Tabuchi A.
Involvement of SRF coactivator MKL2 in BDNF-mediated activation of the synaptic activity-responsive element in the Arc gene. Journal of neurochemistry 2018, September

Kamijo S, Ishii Y, Horigane SI, Suzuki K, Ohkura M, Nakai J, Fujii H, Takemoto-Kimura S, Bito H.
A Critical Neurodevelopmental Role for L-Type Voltage-Gated Calcium Channels in Neurite Extension and Radial Migration. The Journal of Neuroscience 2018, June 38(24); 5551-5566

El-Boustani S, Ip JPK, Breton-Provencher V, Knott GW, Okuno H, Bito H, Sur M.
Locally coordinated synaptic plasticity of visual cortex neurons in vivo. Science 2018, June 360(6395); 1349-1354

Koizumi K, Inoue M, Chowdhury S, Bito H, Yamanaka A, Ishizuka T, Yawo H.
Functional emergence of a column-like architecture in layer 5 of mouse somatosensory cortex in vivo. The journal of physiological sciences : JPS 2018, May

Yamazaki H, Sasagawa Y, Yamamoto H, Bito H, Shirao T.
CaMKIIβ is localized in dendritic spines as both drebrin-dependent and drebrin-independent pools. Journal of neurochemistry 2018, April 146(2); 145-159

<2017>

Okuno H, Minatohara K, Bito H.
Inverse synaptic tagging: An inactive synapse-specific mechanism to capture activity-induced Arc/arg3.1 and to locally regulate spatial distribution of synaptic weights. Seminars in cell & developmental biology 2017, September 77; 43-50

Jenks KR, Kim T, Pastuzyn ED, Okuno H, Taibi AV, Bito H, Bear MF, Shepherd JD.
Arc restores juvenile plasticity in adult mouse visual cortex. PNAS 2017, July 114(34); 9182-9187

Nikolaienko O, Eriksen MS, Patil S, Bito H, Bramham CR.
Stimulus-evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization. Neuroscience 2017, July 360; 68-80

Inokuchi K, Imamura F, Takeuchi H, Kim R, Okuno H, Nishizumi H, Bito H, Kikusui T, Sakano H.
Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses. Nature communications 2017, July 8; 15977

Rapanelli M, Frick L, Bito H, Pittenger C.
Histamine modulation of the basal ganglia circuitry in the development of pathological grooming. PNAS 2017, June 114(25); 6599-6604

Takemoto-Kimura S, Suzuki K, Horigane SI, Kamijo S, Inoue M, Sakamoto M, Fujii H, Bito H.
Calmodulin kinases: essential regulators in health and disease. Journal of neurochemistry 2017, June 141(6); 808-818

Rapanelli M, Frick L, Pogorelov V, Ohtsu H, Bito H, Pittenger C.
Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders. Translational psychiatry 2017, January 7(1); e1013

Honjoh S, de Vivo L, Okuno H, Bito H, Tononi G, Cirelli C.
Higher Arc Nucleus-to-Cytoplasm Ratio during Sleep in the Superficial Layers of the Mouse Cortex. Frontiers in neural circuits 2017, 11; 60

Steward O, Matsudaira Yee K, Farris S, Pirbhoy PS, Worley P, Okamura K, Okuno H, Bito H.
Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice. Frontiers in molecular neuroscience 2017, 10; 435

<2016>

Kim CK, Yang SJ, Pichamoorthy N, Young NP, Kauvar I, Jennings JH, Lerner TN, Berndt A, Lee SY, Ramakrishnan C, Davidson TJ, Inoue M, Bito H, Deisseroth K.
Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain. Nature Methods 2016, April 13(4); 325-328

Horigane S, Ageta-Ishihara N, Kamijo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H.
Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization. Molecular Brain 2016, January 9(1); 8

Gaffield MA, Amat SB, Bito H, Christie JM.
Chronic imaging of movement-related Purkinje cell calcium activity in awake behaving mice. Journal of neurophysiology 2016, January 115(1); 413-422

<2015>

Vousden DA, Epp J, Okuno H, Nieman BJ, van Eede M, Dazai J, Ragan T, Bito H, Frankland PW, Lerch JP, Henkelman RM.
Whole-brain mapping of behaviourally induced neural activation in mice. Brain structuire & function 2015, July 220(4); 2043-2057

Yamamoto K, Tanei Z, Hashimoto T, Wakabayashi T, Okuno H, Naka Y, Yizhar O, Fenno LE, Fukayama M, Bito H, Cirrito JR, Holtzman DM, Deisseroth K, Iwatsubo T.
Chronic optogenetic activation augments aβ pathology in a mouse model of Alzheimer disease. Cell reports 2015 May 11; 859-865

Fukuchi M, Tabuchi A, Kuwana Y, Watanabe S, Inoue M, Takasaki I, Izumi H, Tanaka A, Inoue R, Mori H, Komatsu H, Takemori H, Okuno H, Bito H, Tsuda M.
Neuromodulatory effect of Gαs- or Gαq-coupled G-protein-coupled receptor on NMDA receptor selectively activates the NMDA receptor/Ca2+/calcineurin/cAMP response element-binding protein-regulated transcriptional coactivator 1 pathway to effectively induce. The Journal of Neuroscience 2015 Apr 35; 5606-5624

Fukuchi M, Nakashima F, Tabuchi A, Shimotori M, Tatsumi S, Okuno H, Bito H, Tsuda M.
Class I histone deacetylase-mediated repression of the proximal promoter of the activity-regulated cytoskeleton-associated protein gene regulates its response to brain-derived neurotrophic factor. The Journal of Biological Chemistry 2015 Mar 290; 6825-6836

Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H.
Rational design of a high-affinity, fast, red calcium indicator R-CaMP2. Nature Methods 2015 Jan 12; 64-70 press release

<2014>

Nonaka M, Kim R, Fukushima H, Sasaki K, Suzuki K, Okamura M, Ishii Y, Kawashima T, Kamijo S, Takemoto-Kimura S, Okuno H, Kida S, Bito H.
Region-specific activation of CRTC1-CREB signaling mediates long-term fear memory. Neuron 2014 Oct 84; 92-106 press release

Nonaka M, Kim R, Sharry S, Matsushima A, Takemoto-Kimura S, Bito H.
Towards a better understanding of cognitive behaviors regulated by gene expression downstream of activity-dependent transcription factors. Neurobiol Learn Mem doi: 10.1016/j.nlm.2014.08.010 , 2014.

Kawashima T, Okuno H, Bito H.
A new era for functional labeling of neurons: activity-dependent promoters have come of age. Front Neural Circuits 2014 Apr 23; 8-23

Vousden DA, Epp J, Okuno H, Nieman BJ, van Eede M, Dazai J, Ragan T, Bito H, Frankland PW, Lerch JP, Henkelman RM.
Whole-brain mapping of behaviourally induced neural activation in mice. Brain structure & function DOI 10.1007/s00429-014-0774-0

Nonaka M, Fujii H, Kim R, Kawashima T, Okuno H, Bito H.
Untangling the two-way signaling route from synapses to the nucleus, and from the nucleus back to the synapses. Phil Trans Roy Soc B Biol Sci in press

Ageta-Ishihara N, Miyata T, Ohshima C, Watanabe M, Sato Y, Hamamura Y, Higashiyama T, Mazitschek R, Bito H, Kinoshita M.
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.Nature Communications in press

Kawashima T, Kitamura K, Suzuki K, Nonaka M, Kamijo S, Takemoto-Kimura S, Kano M, Okuno H, Ohki K, Bito H.
Functional labeling of neuronal ensemble and axonal projections in vivo using a synthetic activity-dependent promoter E-SARE. Nature Method 10: 889-895, 2013 [PubMed]

Mikuni T, Uesaka N, Okuno H, Hirai H, Deisseroth K, Bito H, Kano M.
The immediate early gene Arc/Arg3.1 is a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum. Neuron 78: 1024-1035, 2013 [PubMed]

Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H.
Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineurin. Cell Reports. in press.

2012

Endo T, Kakeyama M, Uemura Y, Haijima A, Okuno H, Bito H, Tohyama C.
Executive function deficits and social-behavioral abnormality in mice exposed to a low dose of dioxin in utero and via lactation. PLoS One. 7: e50741, 2012

Watakabe A, Kato S, Kobayashi K, Takaji M, Nakagami Y, Sadakane O, Ohtsuka M, Hioki H, Kaneko T, Okuno H, Kawashima T, Bito H, Kitamura Y, Yamamori T.
Visualization of cortical projection neurons with retrograde TET-off lentiviral vector. PLoS One. 7: e46157, 2012

Kim R, Okuno H, Bito H.
Deciphering the molecular rules governing synaptic targeting of the memory related protein Arc. Commun. Integr. Biol. 5: 496-498, 2012

Okuno H, Akashi K, Ishii Y, Yagishita-Kyo N, Suzuki K, Nonaka M, Kawashima T, Fujii H, Takemoto-Kimura S, Abe M, Natsume R, Chowdhury S, Sakimura K, Worley PF, Bito H.
Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ. Cell 149, 886-898, 2012.

Wei G, Yin Y, Li W, Bito H, She H, Mao Z.
Calpain-mediated degradation of myocyte enhancer factor 2D contributes to excitotoxicity by activation of extrasynaptic N-methyl-D-aspartate receptors. J. Biol. Chem. 287, 5797-5805, 2012.

Yoshida K, Ono M, Bito H, Mikami T, Sawada H.
Plasmodium induced by SU6656, an Src family kinase inhibitor, is accompanied by a contractile ring defect. Cell Biochem Funct. 2011 Oct 27. doi: 10.1002/cbf.1814. [Epub ahead of print]

2011

Negishi-Koga T, Shinohara M, Komatsu N, Bito H, Kodama T, Friedel RH, Takayanagi H.
Suppression of bone formation by osteoclastic expression of semaphorin 4D. Nature Med. 17, 1473-1480, 2011.

Tse D, Takeuchi T, Kakeyama M, Kajii Y, Okuno H, Tohyama C, Bito H, Morris RG.
Schema-dependent gene activation and memory encoding in neocortex. Science 333, 891-895, 2011.

Komatsu T, Johnsson K, Okuno H, Bito H, Inoue T, Nagano T, Urano Y.
Real-time measurements of protein dynamics using fluorescence activation-coupled protein labeling method. J. Am. Chem. Soc. 133, 6745-6751, 2011.

2010

Okuno H.
Regulation and function of immediate-early genes in the brain: beyond neuronal activity markers. Neurosci Res. 69, 175-186, 2010.

Inoue M, Yagishita-Kyo N, Nonaka M, Kawashima T, Okuno H, Bito H.
Synaptic activity-responsive element (SARE): A unique genomic structure with an unusual sensitivity to neuronal activity. Commun Integr Biol. 3: 443-446, 2010.

Takemoto-Kimura, S., Suzuki, K., Kamijo, S., Ageta-Ishihara, N., Fujii, H., Okuno, H., & Bito, H..
Differential roles for CaM kinases in mediating excitation-morphogenesis coupling during formation and maturation of neuronal circuits.　Eur. J. Neurosci. 32, 224-230, 2010.

Bito, H.
The chemical biology of synapses and neuronal circuits. Nature Chem.Biol. 6, 560-563, 2010.

Kim, T.K., Hemberg, M., Gray, J.M., Costa, A.M., Bear, D.M., Wu, J., Harmin, D.A., Laptewicz, M., Barbara-Haley, K., Kuersten, S., Markenscoff-Papadimitriou, E., Kuhl, D., Bito, H., Worley, P.F., Kreiman, G., Greenberg, M.E.
Widespread transcription at neuronal activity-regulated enhancers. Nature 465, 182-187, 2010.

Redondo, R.L., Okuno, H., Spooner, P.A., Frenguelli, B.G., Bito, H. & Morris, R.G.M.
Synaptic tagging and capture: differential role of distinct calcium-calmodulin kinases in protein synthesis-dependent long-term potentiation. J. Neurosci. 30, 4981-4989, 2010.

2009

Ageta-Ishihara, N., Takemoto-Kimura, S., Nonaka, M., Adachi-Morishima, A., Kamijo, S., Suzuki, S., Fujii, H., Mano, M., Blaeser, F., Chatila, T.A., Mizuno, H., Hirano, T., Tagawa, Y., Okuno, H. & Bito, H.
Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade. J. Neurosci. 29, 13720-13729, 2009.

Kawashima, T., Okuno, H., Nonaka, M., Adachi-Morishima, A., Kyo, N., Okamura, M., Takemoto-Kimura, S., Worley, P., Bito, H.
A synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons, Proc. Natl. Acad. Sci. USA 106, 316-321, 2009.

Nonaka M.
A Janus-like role of CREB protein: enhancement of synaptic property in mature neurons and suppression of synaptogenesis and reduced network synchrony in early development. J Neurosci. 29, 6389-6391, 2009..

2008

Bito, H., Takemoto-Kimura, S., Okuno, H.
Activity-dependent gene regulation: How do synapses talk to the nucleus and fine-tune neuronal outputs? in “Molecular Pain” (M. Zhuo ed. Springer). 2008.

2007

Fuse, T., Ohmae, S., Takemoto-Kimura, S., Bito, H.
DCLK1. AfCS/Nature Molecule Pages 　doi:10.1038/mp.a003011.01. 2007.

Takemoto-Kimura, S., Ageta-Ishihara, N., Nonaka, M., Adachi-Morishima, A., Mano, T., Okamura, M., Fujii, H., Fuse, T., Hoshino, M., Suzuki, S., Kojima, M., Mishina, M., Okuno, H., Bito, H.
Regulation of dendritogenesis via a lipid raft-associated Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKIgamma. Neuron 54, 755-770, 2007.

Kiyonaka, S., Wakamori, M., Miki, T., Uriu, Y., Nonaka, M., Bito, H., Beedle, A.M., Mori, E., Hara, Y., De Waard, M., Kanagawa, M., Itakura, M., Takahashi, M., Campbell, K.P., Mori, Y.
The active zone protein RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nature Neurosci. 10, 691-701, 2007.

2006

Chowdhury, S., Shepherd, JD., Okuno, H., Lyford, G., Petralia, RS., Plath, N., Kuhl, D., Huganir, RL. & Worley, PF.
Arc interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron 52, 445-59. 2006.

Sato, K., Suematsu, A., Nakashima, T., Takemoto-Kimura, S., Aoki, K., Morishita, Y., Asahara, H., Ohya, K., Yamaguchi, A., Takai, T., Kodama, T., Chatila, T.A., Bito, H., Takayanagi, H.
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nature Med. 12, 1410-1416, 2006.

Yamana, N., Arakawa, Y., Nishino, T., Kurokawa, K., Tanji, M., Itoh, RE., Monypenny, J., Ishizaki, T., Bito, H., Nozaki, K., Hashimoto, K., Matsuda, M., Narumiya, S.
Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing APC and c-Src. Mol. Cell Biol. 26, 6844-6858, 2006.

Kuriu, T., Inoue, A., Bito, H., Sobue, K., Okabe, S.
Differential control of postsynaptic density scaffolds via actin-dependent and independent mechanisms. J. Neurosci. 26: 7693-7706, 2006.

Ohmae, S., Takemoto-Kimura, S., Okamura, M., Adachi-Morishima, A., Nonaka, M., Fuse, T., Kida, S., Tanji, M., Furuyashiki, T., Arakawa, Y., Narumiya, S., Okuno, H., Bito H.
Molecular identification and characterization of a family of kinases with homology to CaMKI/CaMKIV. J. Biol. Chem. 281, 20427-20439, 2006.

Uemura, K., Kihara, T., Kuzuya, A., Okawa, K., Nishimoto, T., Bito, H., Ninomiya, H., Sugimoto, H., Kinoshita, A., Shimohama, S.
Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin. Biochem Biophys Res Commun. 345, 951-958, 2006.

Nonaka, M., Doi, T., Fujiyoshi, Y., Takemoto-Kimura, S., Bito, H.
Essential contribution of the ligand-binding bB-bC loop of PDZ1 and PDZ2 in the regulation of postsynaptic clustering, scaffolding and localization of PSD-95. J. Neurosci. 26, 763-774, 2006.

Okuno, H. and Bito H.
CREB1. AfCS/Nature Molecule Pages, doi:10.1038/ mp.a000690.01, 2006.

2005

Iki, J., Inoue, A., Bito, H., Okabe, S.
Bidirectional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity. Eur. J. Neurosci. 22, 2985-2994, 2005.

Matsuoka, Y., Furuyashiki, T., Yamada, K., Nagai, T., Bito, H., Tanaka, Y., Kitaoka, S., Ushikubi, F., Nabeshima, T., Narumiya, S.
Prostaglandin E receptor EP1 controls impulsive behavior under stress. Proc. Natl. Acad. Sci. USA 102, 16066-16071, 2005.

Hoshino, M., Nakamura, S., Mori, K., Kawauchi, T., Terao, M., Nishimura, Y.V., Fukuda, A., Fuse, T., Matsuo, N., Sone, M., Watanabe, M., Bito, H., Terashima, T., Wright, C.V.E., Kawaguchi, Y., Nakao, K., and Nabeshima, Y.
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron 47, 201-213, 2005.

2004

Nemoto, T.., Kojima, T.., Oshima, A., Bito, H., Kasai, H.
Stabilization of exocytosis by dynamic F-actin coating of zymogen granules in pancreatic acini. J. Biol. Chem. 279, 37544-37550, 2004.

Suga, H., Takeda, S., Haga, T., Okamura, M., Takao, K., and Takemoto, K.
Stimulation of increases in intracellular calcium and prostaglandin E2 generation in Chinese hamster ovary cells expressing receptor-Gα16 fusion proteins. J. Biochem. 135, 605-613, 2004.

Takeda, S., Okada, T., Okamura, M., Haga, T., Isoyama-Tanaka, J., Kuwahara, H., and Minamino, N.
The receptor-Gα fusion protein as a tool for ligand screening: A model study using a nociceptin receptor-Gαi2 fusion protein. J. Biochem. 135, 597-604, 2004.

Zhang, Q., Okamura, M., Guo, Z.-D., Niwa, S., and Haga, T.
Effects of partial agonists and Mg2+ ions on the interactions of M2 muscarinic acetylcholine receptor and G protein Gαi1 subunit in the M2-Gαi1 fusion protein. J. Biochem. 135, 589-596, 2004.

2003

Bito H.
Dynamic control of neuronal morphogenesis by rho signaling. J Biochem. 134, 315-319, 2003.

Bito H, Takemoto-Kimura S.
Ca2+/CREB/CBP-dependent gene regulation: a shared mechanism critical in long-term synaptic plasticity and neuronal survival. Cell Calcium 34, 425-430, 2003.

Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Furuyashiki T, Arakawa Y, Narumiya S, Bito H.
Molecular cloning and characteriation of CLICK-III/CaMKIg, a novel membrane anchored neuronal CaMK. J. Biol. Chem. 278, 18597-18605, 2003.

Arakawa Y, Bito H, Furuyashiki T, Tsuji T, Takemoto-Kimura S, Kimura K, Nozaki K, Hashimoto N, Narumiya S.
Control of axon elongation via an SDF-1a / Rho / mDia pathway in cultured cerebellar granule neurons. J.Cell Biol. 161, 381-391, 2003.

Matsuoka Y, Furuyashiki T, Bito H, Ushikubi F, Tanaka Y, Kobayashi T, Muro S, Satoh N, Kayahara T, Higashi M, Mizoguchi A, Shichi H, Fukuda Y, Nakao K, Narumiya S.
Impaired adrenocorticotropic hormone response to bacterial bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes. Proc. Nat. Acad. Sci. USA 100, 4132-4137, 2003.

2002

Tokuyama W, Okuno H, Hashimoto T, Li YX, Miyashita Y.
Selective zif268 mRNA induction in the perirhinal cortex of macaque monkeys during formation of visual pair-association memory. J Neurochem. 81, 60-70, 2002.

Furuyashiki T, Arakawa Y, Takemoto-Kimura S, Bito H, Narumiya S.
Multiple spatiotemporal modes of actin reorganization by NMDA receptors and voltage-gated Ca2+ channels. Proc. Natl. Acad. Sci. USA 99, 14458-14463, 2002.

2001

Li YX, Hashimoto T, Tokuyama W, Miyashita Y, Okuno H.
Spatiotemporal dynamics of brain-derived neurotrophic factor mRNA induction in the vestibulo-olivary network during vestibular compensation. J Neurosci. 21, 2738-2748, 2001.

Li YX, Tokuyama W, Okuno H, Miyashita Y, Hashimoto T.
Differential induction of brain-derived neurotrophic factor mRNA in rat inferior olive subregions following unilateral labyrinthectomy. Neuroscience 106, 385-394, 2001.

See V, Boutillier AL, Bito H, Loeffler JP.
Calcium/calmodulin- dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons. FASEB J. 15, 134-144, 2001.

Yamasaki T, Kawaji K, Ono K, Bito H, Hirano T, Osumi N, Kengaku M.
Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum. Development 128, 3133-3144, 2001.

Yamamoto M, Hilgemann DH, Feng S, Bito H, Ishihara H, Shibasaki Y, Yin HL.
Phosphatidylinositol 4,5-bisphosphate induces actin stress-fiber formation and inhibits membrane ruffling in CV1 cells. J Cell Biol. 152, 867-876, 2001.

2000

Tokuyama W, Okuno H, Hashimoto T, Xin Li Y, Miyashita Y.
BDNF upregulation during declarative memory formation in monkey inferior temporal cortex. Nat Neurosci. 3, 1134-1142, 2000.

Hashimoto T, Okuno H, Tokuyama W, Li YX, Miyashita Y.
Expression of brain-derived neurotrophic factor, neurotrophin-3 and their receptor messenger RNAs in monkey rhinal cortex. Neuroscience 95,: 1003-1010, 2000.

Madaule P, Furuyashiki T, Eda M, Bito H, Ishizaki T, Narumiya S.
Citron, a Rho target that affects contractility during cytokinesis. Microsc. Res. Tech. 49, 123-126, 2000.

Bito H, Furuyashiki T, Ishihara H, Shibasaki Y, Ohashi K, Mizuno K, Maekawa M, Ishizaki T, Narumiya S.
A critical role for a Rho-associated kinase p160ROCK in determining axon outgrowth in mammalian CNS neurons. Neuron 26, 431-441, 2000.

Mermelstein PG, Bito H, Deisseroth K, Tsien RW.
Critical dependence of CREB phosphorylation on L-type calcium channels supports a selective response to EPSPs rather than action potentials. J. Neurosci. 20, 266-273, 2000.

Bito H, Deisseroth K, Tsien RW.
Activity-dependent regulation of communication from synapse to nucleus. in "Challenges for Neuroscience in the 21st Century" (O. Hayaishi ed., Japan Scientific Societies Press, Tokyo), pp. 107-120, 2000.

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